北京大学人民医院心血管内科;
目的 探索血小板/淋巴细胞比值（PLR）及左心室射血分数（LVEF）对心房颤动患者导管射频消融术后复发的预测价值。方法 选择2021年9月至2022年11月于北京大学人民医院接受导管射频消融术的158例心房颤动患者，根据术后3～12个月有无复发分为复发组与非复发组。收集患者现病史、既往史、个人史、术前实验室指标及超声心动图指标，采用单因素和多因素Logistic回归分析PLR和LVEF对心房颤动复发的影响，进而采用受试者工作特性（ROC）曲线，评价这两个指标对诊断心房颤动射频消融术后复发的作用，确立诊断界值。分析用PLR和LVEF判断心房颤动复发结果的关联性和一致性（配对χ2检验），根据结果确定联合试验的必要性。结果 两组患者基线资料比较，术前左心房内径（LAD）、PLR、LVEF、三酰甘油（TG）组间差异具有统计学意义（P<0.05）；通过单因素及多因素Logistic回归分析发现，PLR及LVEF是心房颤动射频消融术后复发的独立危险因素；ROC曲线分析显示，PLR及LVEF预测心房颤动射频消融术后复发的曲线下面积（AUC）分别为0.652及0.581，联合指标预测心房颤动射频消融术后复发的AUC为0.682；通过实测数据分析串联试验和并联试验的灵敏度、特异度，串联试验较单一试验特异度提高。结论 术前高PLR和低LVEF可以预测心房颤动射频消融术后复发。根据预测心房颤动射频消融术后复发的临床需求，推荐采用PLR及LVEF串联试验提高诊断效率。
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基本信息:
DOI：
中图分类号:R541.75
引用信息:
[1]陈崇杰,昃峰,段江波等.血小板/淋巴细胞比值及左室射血分数对心房颤动射频消融术后复发的预测价值[J].中国循证心血管医学杂志,2025,17(02):168-174.
基金信息:
国家社会科学基金重大项目(18ZDA086-4)